Dioxacycloalkane compound having renin-inhibitory activity

Details Dioxacycloalkane compound having renin-inhibitory activity Dioxacycloalkane compound having renin-inhibitory activity

1995-02-21

1998-05-12

Zemel, Irina S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

549448, 548215, 548229, 548232, 5483111, 548314, 514336, 514252, 514397, 560 32, 560115, 556420, C07D31728, C07D23364, A61K 31335, C07C21526

Patent

active

057506965

ABSTRACT:
##STR1## wherein A is ##STR2## wherein W is ##STR3## X is --CO-- or --SO.sub.2 --; Y is --CH.sub.2 --, --O-- or --NR.sup.25 --; and R.sup.1 is an aralkyl which may be substituted by lower alkoxy;

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S. Ishibuchi et al., Tetrahedron Letters, 32(29), 3523-3526 (1991).
W. Patt et al., J. Med. Chem., 35(14), 2562-2572 (1992).

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