Diorganopolysiloxane dosage forms for the controlled release of

Details Diorganopolysiloxane dosage forms for the controlled release of Diorganopolysiloxane dosage forms for the controlled release of

1988-02-26

1989-12-12

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424672, A61K 3173, A01N 5912

Patent

active

048866610

ABSTRACT:
Heat-vulcanized silicone dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are shaped from (A) a diorganopolysiloxane matrix resin containing at least two vinyl groups bonded to silicon per molecule and having a viscosity of at least 500,000 mPa.s at 25.degree. C.; (B) at least one organohydropolysiloxane containing at least three hydrogen atoms bonded to silicon per molecule; (C) a reinforcing amount of a filler material therefor; (D) a catalytically effective amount of a platinum group metal catalyst; and (E) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid or liquid state at ambient temperature.

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