Dinucleoside polyphosphate compositions and their...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C514S051000, C514S851000, C514S378000, C514S008100, C514S912000, C536S023500, C536S026230, C536S025600, C424S046000, C424S045000, C424S489000, C546S229000

Reexamination Certificate

active

06867199

ABSTRACT:
The present invention relates to certain novel dinucleoside polyphosphates of general Formulae I, II and III, and formulations thereof which are selective ligands of the P2Y purinergic receptors. Applicants have discovered that dinucleoside polyphosphates of general Formulae I, II and III are effective in clearing retained mucous secretions, balancing tissue hydration and fluid secretion, and/or inhibiting or preventing early stages of platelet activation, platelet degranulation, and platelet aggregation.

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