Dinitrogen heterocyclic derivatives N-substituted by a biphenylm

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514257, 514387, 514386, 514380, 514383, 514384, 514364, 514363, 544231, 544319, 5483007, 5483111, 5483235, 5483241, 548243, 5482632, 5482662, 548132, 548133, 548138, 548144, C07D23336, C07D23936, A61K 31505, A61K 31415

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active

052683753

ABSTRACT:
This invention relates to compounds of formula ##STR1## in which: R.sub.1 and R.sub.2 are similar or different and are each independently hydrogen or a group selected from CO.sub.2 N.dbd.C(NH.sub.2).sub.2, CONHNHCONH.sub.2, CONHNHCSNH.sub.2, C(OC.sub.2 H.sub.5).dbd.NCO.sub.2 CH.sub.3, COCH.sub.2 CO.sub.2 H.sub.5, N(OH)-CONHCOOC.sub.2 NCO.sub.2 CH.sub.3, COCH.sub.2 CO.sub.2 H.sub.5, N(OH)-CONHCOOC.sub.2 H.sub.5, C(OC.sub.2 H.sub.5).dbd.NH or a nitrogen heterocycle; with the proviso that at least one of the substituents R.sub.1 or R.sub.2 is other than hydrogen;

REFERENCES:
patent: 4675403 (1987-06-01), Abou-Gharbia
patent: 5100897 (1992-03-01), Allen et al.

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