Dimethylglycine enhancement of antibody production

Details Dimethylglycine enhancement of antibody production Dimethylglycine enhancement of antibody production

1991-02-01

1992-06-02

Doll, John

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

43524027, 4352403, C12P 2108, C12N 502, C12N 516

Patent

active

051186187

ABSTRACT:
N,N-dimethylglycine, along or in combination with mitogen, increases the antibody productivity of antibody-producing cell cultures.

REFERENCES:
patent: 4196265 (1980-04-01), Koprowski et al.
patent: 4271145 (1981-06-01), Wands et al.
patent: 4364937 (1982-12-01), Kune et al.
Graber et al., Immunomodulating Properties of Dimethyglycine in Humans J. Infectious Diseases, vol. 143, No. 1, pp. 101-105, 1981.
Tsiagbe et al., Poultry Sci. 66:1138-1146 and 66:1147-1154 (1987).
Gorski et al., FASEB. J. 5:2287-2291 (1991).
Wing-Keung et al., Immunobiology, 180:23-32 (1989).

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