Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-01-06
1996-12-10
Guzo, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 405, 536 231, 546165, C12Q 168, G01N 3352, C07H 2102, C07H 2104
Patent
active
055829775
ABSTRACT:
The invention relates to dimers of unsymmetrical cyanine dyes, typically dimers of benzthiazole or benzoxazole derivatives, that exhibit enhanced fluorescence on binding with DNA or RNA, The dimers generally have the formula: ##STR1## where R.sup.1 and R.sup.2, which may be the same or different, are alkyl groups having 1-6 carbons;
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Ausubel, et al., Short Protocols in Molecular Biology, p. 359, John Wiley & Sons.
Haugland Richard P.
Johnson Iain D.
Yue Stephen T.
Guzo David
Helfenstein Allegra J.
Molecular Probes, Inc.
Skaugset Anton E.
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