Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-03-21
2010-10-05
Saeed, Kamal A (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S422000, C548S255000
Reexamination Certificate
active
07807699
ABSTRACT:
The invention provides small molecule mimics of the Smac peptide that are dimer- or dimer-like compounds having two amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
REFERENCES:
patent: 7547724 (2009-06-01), Laurent et al.
patent: 7589118 (2009-09-01), Laurent et al.
patent: 2005/0197403 (2005-09-01), Harran et al.
patent: 2006/0025347 (2006-02-01), Condon et al.
patent: WO-03/086470 (2003-10-01), None
Li et al. (Science (2004) 305:1471-1474; provided by Applicants in the IDS of May 18, 2009.
International Search Report for PCT/US2007/064569, mailed Jan. 11, 2008, 4 pages.
Bockbrader et al., Oncogene (2005) 24:7381-7388.
Du et al., Cell (2000) 102:33-43.
Li et al., Science (2004) 305:1471-1474.
Makin et al., Cell Tissue Res. (2000) 301:143-152.
Verhagen et al., Cell (2000) 102:43-53.
Vucic et al., Biochem. J. (2005) 385:11-20.
Chandrakumar Nizal
Hanson Gunnar J.
Harran Susan
Thomas David
Joyant Pharmaceuticals, Inc.
Osman Richard Aron
Rodriguez-Garcia Valerie
Saeed Kamal A
LandOfFree
Dimeric pyrrolidine amide-containing small molecule... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dimeric pyrrolidine amide-containing small molecule..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dimeric pyrrolidine amide-containing small molecule... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4158540