Dimeric compounds and their use as anti-viral agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

07468388

ABSTRACT:
The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2-C9alkyl C3-8cycloalkyl, C1-C4alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.

REFERENCES:
patent: 6548476 (2003-04-01), Wu et al.
patent: WO 98/21243 (1998-05-01), None
patent: WO 00/55149 (2000-09-01), None
patent: WO 02/20514 (2002-03-01), None
Fleming, DM “Managing influenza: amantadine, rimanadine and beyond”, PMID 11351773 (2001).

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