Dimeric compounds and their use as anti-viral agents

Details Dimeric compounds and their use as anti-viral agents Dimeric compounds and their use as anti-viral agents

2007-05-08

2007-05-08

Owens, Amelia A. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C549S424000, C549S425000

Reexamination Certificate

active

10494242

ABSTRACT:
The invention relates to compounds of general formula (I), in which: R is an amino or guanidino group; R2is acetyl or trifluoroacetyl; n and q are either the same or different and selected from 0, 1 or 2; and X is an optionally substituted phenyl, optionally substituted naphthyl or optionally substituted phenyl-Y-optionally substituted phenyl in which Y is selected from a covalent bond, CH2, CH2CH2, O or SO2, or a pharmaceutically acceptable derivative thereof, with the proviso that when X is phenyl or naphthyl, n and q are both 2 and when X is phenyl-Y-phenyl in which Y is a covalent bond, then n and q are not both 0, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection

REFERENCES:
patent: 6548476 (2003-04-01), Wu et al.
patent: WO 00/55149 (2000-09-01), None
patent: WO 02/20514 (2002-03-01), None
Fleming, DM Managing influenza: amantadine, rimantadine and beyond, PMID: 11351773, (2001).

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