Dilution and mixing cartridge

Details Dilution and mixing cartridge Dilution and mixing cartridge

1989-04-13

1992-04-14

Warden, Robert J.

Chemistry: analytical and immunological testing

Including sample preparation

Dilution

436180, 436165, 422100, 422 58, 422102, 422 8205, 422106, 422105, G01N 2100, G01N 110

Patent

active

051048132

ABSTRACT:
A dilution and mixing cartridge is provided that allows single (or multiple) dilutions of a sample with a diluent in a disposable cartridge in which a measurement, such as optical density, is made. Addition of sample to the device automatically measures the sample, and addition of diluent automatically causes a fixed ratio of sample and diluent to enter a receiving chamber, in which mixing and measurement can take place. A number of preferred embodiments are provided in which the diluent application site is located at a vertical height below the sample application site, flow directing chambers are provided to control flow of desired volumes of sample or diluted sample at the appropriate locations in the device and to direct excess sample and diluent to waste locations, or control mechanism are provided at flow directing chambers and other internal locations to verify correct operation of the device.

REFERENCES:
patent: 4868129 (1989-09-01), Gibbons et al.
patent: 4876203 (1989-10-01), Guigan
patent: 4883763 (1989-11-01), Holen et al.
patent: 4985204 (1991-01-01), Klose et al.
patent: 4999304 (1991-03-01), Robertson

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