Diluent and method for potentiometric assay of liquids

Chemistry: electrical and wave energy – Processes and products

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2524081, 26050117, 436 74, 436 79, 436174, 436179, 564503, G01N 2746, G01N 100

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active

044167350

ABSTRACT:
A diluent and a method of assaying are described, by which the ionic strength range of the liquid that is to be assayed potentiometrically, is compressed. The diluent comprises a predetermined concentration of (a) a protonated water-soluble organic amine having (i) a pKa greater than or equal to 9.3, and (ii) a hydroxyalkyl of 1 to 5 carbon atoms, bonded to the nitrogen of the amine, wherein the oxygen-to-carbon bond of the hydroxy is no more than two bonds removed from the nitrogen, and (b) an acid anion.

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Jack H. Ladenson, Clin. Chem., 25, 5, 757, (1979).

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