Drug – bio-affecting and body treating compositions – Anti-perspirants or perspiration deodorants
Patent
1990-07-30
1995-08-15
Ore, Dale R.
Drug, bio-affecting and body treating compositions
Anti-perspirants or perspiration deodorants
252106, 252107, 424 66, 424 67, 424 68, 428190, 428227, 512 23, 514844, 514847, 514937, 514938, A61K 732, B32B 300, C11D 348, C11D 950
Patent
active
054417279
ABSTRACT:
The present invention provides deodorant compositions for controlling malodor from perspiration comprising a safe an effective amount of a 1,3-diketone compound having the general formula: ##STR1## wherein each W is independently selected from the group consisting of O, S and (CH.sub.2).sub.n, wherein n=1-3; and each X is independently selected from the group consisting of hydrogen, halogen, substituted or unsubstituted alkyl having from about 1 to about 5 carbon atoms, or two X moieties are covalently bonded to form a substituted or unsubstituted alkyl, heteroalkyl, aryl or heteroaryl ring having from about 3 to about 12 atoms including from 0 to about 3 heteroatoms in the ring; and a topical carrier; whereby the composition is suitable for topical application to the skin or to articles of clothing worn in the vicinity of the skin.
Methods for controlling malodor comprising depositing on skin in the axilla or crotch region, or to articles of clothing worn in the vicinity of the skin of a safe and effective amount of a 1,3-diketone of the present invention, are also provided.
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Johnson, B. C., T. S. Hamilton and H. H. Mitchell, "The Excretion of Pyridoxine, `Pseudopyridoxine`, and 4 Pyridoxic Acid in the Urine and Sweat of Normal Individuals", J. Biol. Chem., vol. 158 (1945), pp. 619-623.
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Bush Rodney D.
Chatterjee Ranjit
Corstanje Brahm J.
Graff IV Milton B.
Howell John M.
Ore Dale R.
The Procter & Gamble & Company
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