Dihydroxybenzisoxazolin-3-yl-substituted-5-nitroimidazoles as an

Details Dihydroxybenzisoxazolin-3-yl-substituted-5-nitroimidazoles as an Dihydroxybenzisoxazolin-3-yl-substituted-5-nitroimidazoles as an

1978-01-06

1979-03-13

Rush, Raymond V.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

260307DA, 548339, C07D26120, A61K 3142

Patent

active

041443454

ABSTRACT:
Dihydroxybenzisoxazolin-3-yl-substituted-1-methyl-5-nitroimidazoles having the hydroxy- groups on adjacent 4,5-; 5,6- or 6,7-positions of the isoxazolin group. These compounds have antibacterial and antiprotozoal activity in humans and animals. They are particularly active against trypanosomiasis and trichomoniasis.

REFERENCES:
patent: 3711495 (1973-01-01), Kulsa et al.
Morrison et al-"Organic Chemstry"-Allyn & Bacon, Inc. (1959)-p. 651.

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