Dihydrotestosterone for use in androgenotherapy

Details Dihydrotestosterone for use in androgenotherapy Dihydrotestosterone for use in androgenotherapy

1996-07-08

1997-07-15

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

A61K 3156

Patent

active

056483503

ABSTRACT:
The present invention is directed to the administration of dihydrotestosterone (DHT) for preventing prostate cancer in male patients more than 50 years old and of reducing levels of plasma-borne sex hormone binding globulins (SHBG) in male patients having elevated levels thereof.

REFERENCES:
patent: 2927921 (1960-03-01), Oliveto et al.
patent: 4956357 (1990-09-01), Keenan et al.
Geller, J. et al., "DHT in Prostate Cancer Tissue --A Guide to Management and Therapy", The Prostate, vol. 6, No. 1, 1985, pp. 19-25.
Pollard, M. et al., "Dihydrotestosterone Does Not Induce Prostate Adenocarcinoma in L-W Rats", The Prostate, vol. 10, No. 4, 1987, pp. 325-331.
Pollard, M. et al., "Prevention and Treatment of Experimental Prostate Cancer in Lobound-Wistar Rats. I. Effects of Estradiol, Dihydrotestosterone, and Castration", The Prostate, vol. 15, No. 2, 1989, pp. 95-103.
Raynaud, J. P. et al., "Cancer de la Prostate: Bases Biologiques pour l'Emploi d'un Antiandrogene dans le Traitement", Bulletin du Cancer, vol. 73, No. 1, 1986, pp. 36-46.
Kuhn et al., J. Clin. Endocrinol. Metab., 58(2), pp. 231-235 (Biosis Abstract No. 7786041). (1984).
Kuhn et al., Contracept. Fertil. Sex., 14 (11), pp. 1031-1036 (Biosis Abstract No. 83111397). (1986).
Kuhn et al., Presse Med., 12, No. 1, pp. 21-25 (Derwent Abstract No. 83-13873) (1983).
Kuhn et al., Clin. Endocrinol., 19, No.4, pp. 513-520 (Derwent Abstract No. 84-09329) (1983).

Affiliated with

Also associated with

Rating

Dihydrotestosterone for use in androgenotherapy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dihydrotestosterone for use in androgenotherapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dihydrotestosterone for use in androgenotherapy will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1492457