Dihydropyrrolo[1,2-b]isoquinolinedione oximes

Details Dihydropyrrolo[1,2-b]isoquinolinedione oximes Dihydropyrrolo[1,2-b]isoquinolinedione oximes

1986-11-04

1987-06-02

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D47104

Patent

active

046705627

ABSTRACT:
There is disclosed novel compounds of the formula ##STR1## where X is H, halogen, loweralkyl, loweralkoxy, -CF.sub.3, or -OH; R is H, loweralkyl, arylloweralkyl, diarylloweralkyl, loweralkanoyl, arylloweralkanoyl or diarylloweralkanoyl; and R.sub.1 is H.sub.2, O or --NR.sub.2 R.sub.3, R.sub.2 and R.sub.3 being independently H or loweralkyl, or taken together with the nitrogen atom to which they are attached constitute ##STR2## R.sub.4 in turn being H, loweralkyl, hydroxyloweralkyl, aryl, arylloweralkyl or diarylloweralkyl or pharmaceutically acceptable acid addition salts thereof, which are useful for enchancing memory.

REFERENCES:
patent: 4476131 (1984-10-01), Eggler et al.
patent: 4595688 (1986-06-01), Maryanoff

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