Dihydropyridines and use thereof in treating hypertension and is

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546321, A61K 3144, C07D21190

Patent

active

048065579

ABSTRACT:
A compound of the formula: ##STR1## or a pharmaceutically acceptable salt thereof, wherein R.sup.1 is amino, hydroxy, alkoxy, phenoxy or benzyloxy, useful in the treatment of hypertension, angina, renal impairment or acute renal failure.

REFERENCES:
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S. Wilk et al., J. Pharm. Exp. Therap., 206, 227 (1978).
M. Orlowski et al., J. Pharm. Exp. Therap., 212, 167 (1980).
J. F. M. Smits et al., J. Pharm. Exp. Therap., 232 845 (1985).
F. N. Minard et al., J. Chem. Pharmacology, 29, 69 (1980).

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