Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-05-08
1997-09-16
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514332, 546194, 546263, A61K 31445, C07V21186
Patent
active
056681518
ABSTRACT:
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of piperidine and tetrahydropyridine derivatives of 4-phenyl-1,4-dihydropyridines of Formula I. ##STR1## As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
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Serradeil-LeGal et al, Society for Neuroscience, 1994, abstract No. 376.14.
Rudolf et al, European Journal of Pharmacology, 1994, 271, R11-13.
Bruce Marc
Johnson Graham
LeBoulluec Karen
Poindexter Graham S.
Sloan Charles P.
Bristol--Myers Squibb Company
Dahlen Garth M.
Ivy C. Warren
Ryan Richard P.
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