Dihydropyridine antiallergy agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514290, 514300, 514302, 514303, 544279, 546111, 546113, 546117, 546119, 546165, A61K 31505, C07D47104

Patent

active

052486818

ABSTRACT:
##STR1## Platelet activating factor antagonists of formula (I), in which R.sup.2 is optionally substituted phenyl, R.sup.1 is H, alkyl or arylalkyl, Het is an optionally substituted N-containing heterocyclic group optionally fused to a phenyl or a further heterocyclic ring, and Z completes an optionally substituted carbocyclic or heterocyclic ring having a carbonyl group attached to the 5-position of the dihydropyridine ring. The compounds are useful for treating allergic and inflammatory conditions.

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