Dihydropyridine-5-phosphonic acid cyclic ester

Details Dihydropyridine-5-phosphonic acid cyclic ester Dihydropyridine-5-phosphonic acid cyclic ester

1987-07-24

1989-06-27

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544337, C07D40112, A61K 3144

Patent

active

048430765

ABSTRACT:
An optical isomer of a compound having the formula: ##STR1## wherein the two methyl groups at 4- and 6-positions of the dioxaphosphorinane ring assume trans configurations to each other, which has a levo-rotatory angle of optical rotation attributable to the asymmetric carbon atom at 4-position of the dihydropyridine ring, and a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 4380547 (1983-04-01), Materne
patent: 4510310 (1985-04-01), Wehinger et al.
patent: 4576934 (1986-03-01), Seto et al.
Hackh's Chemical Dictionary, 4th Edition, p. 574.

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