Dihydropyridine-3,5-dicarboxylic acid ester derivatives

Details Dihydropyridine-3,5-dicarboxylic acid ester derivatives Dihydropyridine-3,5-dicarboxylic acid ester derivatives

1994-05-05

1995-10-31

Fan, Jane

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D40112

Patent

active

054630649

ABSTRACT:
A dextro-rotatory optical isomer of diastereoisomer A of (.+-.)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzylpyrrolidin-3-yl)ester 5-methyl ester is provided having the formula ##STR1## and wherein the melting point of the hydrochloride of the dextro-rotatory optical isomer is 223.degree. to 230.degree. C. (decomp.), or a pharmaceutically acceptable acid addition salt thereof.

REFERENCES:
patent: 5364872 (1994-11-01), Tamazawa et al.
Berge et al. Journal of Pharmaceutical Science Jan. 1977. vol. 66. No. 1. pp. 1-16.

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