Dihydropyridine-3,5-dicarboxylic acid ester derivatives

Details Dihydropyridine-3,5-dicarboxylic acid ester derivatives Dihydropyridine-3,5-dicarboxylic acid ester derivatives

1992-01-23

1994-11-15

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546281, C07D40112, A61K 3144

Patent

active

053648722

ABSTRACT:
The diastereoisomer A of a dihydropyridine-3,5-dicarboxylic acid ester derivative is provided as well as its pharmaceutically acceptable acid addition salts. The invention further discloses a process for producing the compounds and their use as medicaments in imparting vasodilating activity.

REFERENCES:
patent: 4220649 (1980-09-01), Kojima et al.
patent: 4380547 (1983-04-01), Materne
patent: 4510310 (1985-04-01), Wehinger et al.
patent: 4578467 (1986-03-01), Bonacchi et al.
Morrison, R. T. et al "Organic Chemistry" Third Edition pp. 135, 235-237 (1978).
Streitwieser, A. et al "Introduction to Organic Chemistry" pp. 122-124 (1976).
Merck Index 11th edition pp. 1282-1283, 1989.
Wade Jr. Organic Chemistry Prentice-Hall Inc. 1987. p. 349.

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