Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1989-03-02
1991-02-12
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
514183, 514410, 540145, A61K 3140, A61K 4900, C07D48722
Patent
active
049922572
ABSTRACT:
This invention provides novel compounds for therapy of tumors susceptible to necrosis when an appropriate compound is administered followed by illumination with light of a wavelength absorbed by the compound, the compounds being dihydro porphyrins of the formula, or the corresponding tetra-hydro prophyrins: ##STR1## where n=1 to 3 and each substitutent R, the same or different and at the same or different position in its respective substituent phenyl ring, is an hydroxy group.
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Ciba Foundation Symposium, 1989, pp. 34 to 39.
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Journal of the American Chemical Society, vol. 95, No. 17, Aug. 22, 1973, pp. 5738-5741, H. W. Whitlock et al., "Behavior of Di- and Tetrahydro . . . ".
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Berenbaum Morris C.
Bonnett Raymond
Efamol Holdings PLC
Shah Mukund J.
Ward E. C.
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