Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ketone doai
Reexamination Certificate
2005-05-24
2005-05-24
Levy, Neil S. (Department: 1616)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ketone doai
C424S405000, C424S406000, C424SDIG001, C514S692000, C514S919000
Reexamination Certificate
active
06897244
ABSTRACT:
Two derivatives of nootkatone, tetrahydronootkatone and 1,10-dihydronootkatone, are surprisingly effective as repellents of termites and mosquitos. Tetrahydronootkatone and 1,10-dihydronootkatone were shown to effectively repel termites at concentrations as low as 2 μg/ml and 12.5 μg/ml, respectively. Tetrahydronootkatone was shown to repel mosquitos at a concentration of 5%. Tetrahydronootkatone is an effective repellent of termites either by itself or as an addition to other substrates, including mulches made from wood products or other cellulose-containing material. Tetrahydronootkatone or 1,10-dihydronootkatone can be used to protect construction wood from attack by Formosan subterranean termites, either alone or used in combination with other compounds known to repel termites. It is also believed that these compounds will prove effective in repelling ants, ticks, and cockroaches. These derivatives of nootkatone are non-toxic to humans and other mammals and environmentally safe.
REFERENCES:
patent: 3835192 (1974-09-01), Van Der Linde et al.
patent: 4921696 (1990-05-01), Vander Meer et al.
patent: 4933371 (1990-06-01), Hink et al.
patent: 4937073 (1990-06-01), Fujikura et al.
patent: 5109022 (1992-04-01), Jeanne et al.
patent: 5227163 (1993-07-01), Eini et al.
patent: 5303523 (1994-04-01), Hand et al.
patent: 5411992 (1995-05-01), Eini et al.
patent: 5591435 (1997-01-01), Vaccarello-Dunkel et al.
patent: 5609879 (1997-03-01), Myles
patent: 5696158 (1997-12-01), Oliver
patent: 5802779 (1998-09-01), Hulls et al.
patent: 5847226 (1998-12-01), Muller et al.
patent: 5874097 (1999-02-01), Henderson et al.
patent: 5977186 (1999-11-01), Franklin
patent: 6130253 (2000-10-01), Franklin et al.
patent: 6566562 (2003-05-01), Wohrle et al.
patent: 6624125 (2003-09-01), Trage et al.
patent: 6673756 (2004-01-01), Sonnenberg et al.
patent: 20020055453 (2002-05-01), Eh et al.
patent: 20020064203 (2002-05-01), Eh et al.
patent: 20030068295 (2003-04-01), Rohde et al.
patent: 20040001891 (2004-01-01), Smith et al.
patent: 1 033 076 (2000-09-01), None
patent: 0128343 (2001-04-01), None
Andersen, N., “Biogenetic implications of the antipodal sesquiterpenes of vetiver oil,” Phytochemistry, vol. 9, pp. 145-151 (1970).
Andersen, N.H. et al., “Prezizaene and the biogenesis of zizaene,” Chemistry and Industry, pp. 62-63 (1971).
Chen, J. et al., “Isolation and identification of 2-phenoxyethanol from a ballpoint pen as a trail-following substance ofCoptotermes formosanusShiraki and Reticulitermes spp.”, J. Entomol. Sci., vol. 33, pp. 97-105 (1998).
Chen, J. et al., “Termites fumigate their nests with naphthalene,” Nature, vol. 392, pp. 558-559 (1998).
Erdtman, H. et al., “The Chemistry of the Natural Order Cupressales XVIII: Nootkatone, a new sesquiterpene type hydrocarbon from the heartwood ofChamaecyparis nootkatensis(Lamb.) Spach.,” Acta Chem. Scand., vol. 11, pp. 1157-1161 (1957).
Erdtman, H. et al., “The Chemistry of the Natural Order Cupressales 46. The structure of nootkatone,”Acta Chem. Scand., vol. 16, pp. 1311-1314 (1962).
Grace, J.K., “Natural resistance of Alaska-cedar, redwood, and teak to Formonsan subterranean termites,” Forest Products Journal, vol. 44, pp. 41-45 (1994).
Ibrahim, S.A. et al., “Efficacy of nootkatone, dihydronootkatone, and tetrahydronootkatone on the Formosan subterranean termite (Isoptera: Rhinotermitidae),” to be submitted to Journal of Economic Entomology, 2002.
Isman, M., “Biopesticides based on phytochemicals,” Advances in Biopesticide Research, pp. 1-12 (2000).
Isman, M., “Pesticides based on plant essential oils,” Pesticide Outlook, vol. 10, pp. 68-72 (1999).
Kaiser, R. et al., “Biogenetically significant components in vetiver oil,” Tetrahedron Letters, vol. 20, pp. 2009-2012 (1972).
Lin, Tien-shu et al., “The effects ofCinnamomumspp. oils on the control of the termiteCoptotermes formosanusShiraki,” Taiwan For. Res. Inst. New Series, vol. 10, pp. 459-464 (1995).
Maistrello, D. et al., “Comparative effects of vetiver oil, nootkatone and Disodium Octoborate Tetrahydrate onCoptotermas formosanusand its symbiotic fauna,” accepted for publication by Pest Management Science, 2002.
Maistrello, L. et al., “Effects of nootkatone and a borate compound on Formosan subterrean termite (Isoptera: Rhinotermitidae) and its symbiont protozoa,” J. Entomol. Sci., vol. 36, pp. 229-236 (2001).
Maistrello, L. et al., “Effects of vetiver oil and its constituents onCoptotermes formosanusand its symbiotic fauna,” poster presentation at XXI International Congress of Entomology, Iguassu Falls, Brazil, Aug. 20-26, 2000.
Maistrello, L. et al., “Efficacy of Vetiver Oil and Nootkatone as Soil Barriers Against Formosan Subterranean Termite (Isoptera: Rhinotermitidae),” J. Econ. Entomol., vol. 96, No. 6, pp. 1532-1537 (2001).
Miyazawa, M. et al., “Insecticidal sesquiterpene fromAlpinia oxyphyllaagainstDrosophila melanogaster,” J. Agric. Food Chem., vol. 48, pp. 3639-3641 (2000).
Stevens, K.L. et al., “Odour character and threshold values of nootkatone and related compounds,” J. Sci. Food Agric., vol. 21, pp. 590-593 (1970).
Zhu, B. et al., “Evaluation of vetiver oil and seven insect-active essential oils against Formosan subterranean termites,” J. Chem. Ecol., vol. 27, pp. 1617-1625 (2001).
Zhu, B. et al., “Nootkatone is a repellent for Formosan subterranean termites (Coptotermes formosanus),” Journal of Chemical Ecotogy, vol. 27, pp. 523-531 (2001).
Henderson Gregg
Laine Roger A.
Zhu Betty C. R.
Board of Supervisors of Louisiana State University and Agricultu
Davis Bonnie J.
Levy Neil S.
Runnels John H.
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