Dihydroimidazo[5.1-a]-beta-carboline derivatives, method for...

Details Dihydroimidazo[5.1-a]-beta-carboline derivatives, method for... Dihydroimidazo[5.1-a]-beta-carboline derivatives, method for...

2007-11-06

2007-11-06

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S064000

Reexamination Certificate

active

10478002

ABSTRACT:
The invention concerns dihydroimidazo[5,1-a]-β-carboline compounds of general formula (I)wherein in particular, R1, R2, R3, R4, R6and R7, identical or different, independently of one another, present a hydrogen, halogen atom, an alkyl, hydroxyl, alkoxy, trihalogenoalkyl, alkylamino, dialkylamino, aryl, arylalkyl, carboxy, alkylcarbonyloxy, acyl, aryloxy or arylalkoxy group; R5represents a hydrogen atom, an alkyl or arylalkyl group; and their isomers as well as their addition salts to a pharmaceutically acceptable acid. The inventive compounds are for use in medicine, in particular as hypnotics.

REFERENCES:
patent: 6048868 (2000-04-01), Fourtillan et al.
patent: WO 95/24191 (1995-09-01), None
patent: WO 95/24191 (1995-09-01), None
patent: WO 96/08490 (1996-03-01), None
patent: WO 96/08490 (1996-03-01), None
patent: WO 99/47521 (1999-09-01), None
patent: WO 99/47521 (1999-09-01), None
Goodman & Gilman's The Pharmacological Basis of Therapeutics, 10thedition, McGraw-Hill, New York, New York, 2001, Chapter 17, pp. 399-427.
ADA Sedative Hypnotics, http://www.well.com/user/woa/fsseda.htm, Jun. 9, 2006.
Hypnotic, http://en.wikipedia.org/wiki/Hypnotic, Jun. 9, 2006.
MeReC Bulletin, vol. 15, No. 5, Apr. 2005, published by the NHS, pp. 17-20.
Trujillo et al, Drugs and the Brain, California State University, “Sedative-Hypnotics,” http://www/csusm.edu/DandB/Sedatives.html, Jun. 6, 2006.
Medline Plus, Medical Encyclopedia: Hypnotics, http://www.nlm.nih.gov/medlineplus/print/ency/article/002376.htm, Jun. 9, 2006.
Sedative-Hypnotics, Dec. 23, 2000, http://www.toad.net/˜arcturus/dd/sedative.htm, Jun. 9, 2006.
Crankshaw, Hypnotics in infusion anaesthesia, “Anaesth Intensive Care,” Feb. 1987, 15(1) 90-66, abstract at http://www.general-anaesthesia.com/hypnotics.html, Jun. 9, 2006.
Hypnotics, http://www.humed.com/humc—ency/ency/article/002376.htm, Jun. 9, 2006.
Database Chemical Abstracts Service, Abstract XP-002185124; Kanaoka, Yuichi et al., “Amino acids and Peptides. II. Cyclodehydration of some tryptophan-dipeptides and their derivatives with a . . . ”
J. Elliott,J. Org. Chem., (1962), vol. 27, pp. 3302-3305, “Synthesis of Imidazo[5,1-α]isoquinoline and β-Carboline Derivatives.”
Kanaoka, Yuichi et al., “Amino Acids and Peptides. II. Cyclodehydration of Some Tryptophan-Dipeptides and Their Derivatives with a Polyphosphate Ester,” Chemical Abstracts Service, Columbus, Ohio, Database Accession No. 68:78590 XP002185124 & Tetrahedron (1968), 24(6), 2591-4.

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