Dihydrodipyrazolopyridinone inhibitors of B7-1

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S292000, C514S275000, C514S258100, C514S252040, C546S082000, C544S238000, C544S331000, C544S333000

Reexamination Certificate

active

06900223

ABSTRACT:
The present invention provides a compound of formula I and the use thereof for the immunotherapeutic treatment of transplant rejection, autoimmune disease or graft vs. host disease.

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Ian T. Forbes et al., Journal of Medicinal Chemistry, 1990, vol. 33, 2640-2645.
Erbe, D. V.; Wang, S.; Xing, Y.; and Tobin, J. F.; The Journal of Biological Chemistry (2002), vol. 277, 7363-7368.

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