Dihydrodibenzisoquinolinediones

Details Dihydrodibenzisoquinolinediones Dihydrodibenzisoquinolinediones

1996-08-19

1997-12-30

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 76, A61K 3147

Patent

active

057030898

ABSTRACT:
Novel bis-1,2-dihydro-3H-dibenzisoquinoline-1,3-diones and their salts, processes for their preparation, pharmaceutical compositions containing them and methods of using them to treat malignancies, mainly human solid tumor carcinomas.

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patent: 5554622 (1996-09-01), Brana et al.
patent: 5616589 (1997-04-01), Keilhauer et al.
Sami et al, Jour. Med Chem vol. 36 pp. 765-770, 1993.
Brana et al. AntiCancer Drug Design, vol. 8 pp. 257-268, 1993.
Miller et al BioOrg & Med. Chem. Lett. vol. 4 No. 13 pp. 1643-1648, 1994.

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