Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1990-09-06
1992-05-26
Cintins, Marianne
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
5442375, 544171, 544173, 544174, 544175, 544176, C07D29510
Patent
active
051169797
ABSTRACT:
Dihydrocaffeic acid derivatives are here disclosed which are applicable as medicines having excellent absorbency in the case of oral administration and good concentration retention in blood.
The disclosed compounds have the function to induce the production and secretion of a nerve growth factor (NGF) in the brain tissue, and therefore they are effective as medicines for the progression inhibition and therapy of regressive disorders of the central nervous system.
REFERENCES:
patent: 4053509 (1977-11-01), Faro et al.
patent: 4529604 (1985-07-01), Kaiser
Organic Synthesis, Coll. vol. 3, pp. 575-576, John Wiley & Sons.
Fiat Final Report No. 1313, p. 222 (1948).
Fukazawa Nobuyuki
Iizuka Hajime
Miyama Yukio
Yano Osamu
Cintins Marianne
Mitsui Toatsu Chemicals Incorporated
Nguyen Jessica H.
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