Dihydrobenzofuran and related compounds useful as anti-inflammat

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514456, 514462, 514469, 549 12, 549 23, 549 53, 549 57, 549345, 549355, 549404, 549462, 544 31, 5483114, A61K 3134, C07D30779

Patent

active

056840314

ABSTRACT:
A compound having the structure: ##STR1## wherein (a) n is from 1 to about 3;

REFERENCES:
patent: 3551456 (1970-12-01), Bicoch et al.
patent: 4130666 (1978-12-01), Moore
patent: 4398028 (1983-08-01), Neumann
patent: 4470440 (1984-09-01), Thor
patent: 4613611 (1986-09-01), Floyd, Jr. et al.
patent: 4670457 (1987-06-01), Doria et al.
patent: 4708966 (1987-11-01), Loomans et al.
patent: 4849428 (1989-07-01), Dobson et al.
patent: 4857516 (1989-08-01), Terao et al.
patent: 4966907 (1990-10-01), Caldwell et al.
patent: 4966973 (1990-10-01), Goto
patent: 4975457 (1990-12-01), Rupprechet et al.
patent: 4982006 (1991-01-01), Hudec
patent: 5091533 (1992-02-01), Belanger et al.
patent: 5518994 (1996-05-01), Kawamura et al.
J. Herbert Hall et al., "Syntheses and Photophysical Properties of Some 5(2)-Aryl-2(5)-(4-pyridyl)oxazoles and Related Oxadizoles and Furans", Journal of Heterocyclic Chemistry, vol. 29, No. 5, 1992, pp. 1245-1273.
Jye-Shane Yang, et al., "Electrochemical Reduction of Substituted .alpha.,.alpha., .alpha.-Trifluoroacetophenoens. Linear Relationship Between Cyclic Voltammetric Peak Potentials and Hammett Substituent Constants", Journal of Physical Organic Chemistry, vol. 3, 1990; pp. 723-731.
M.L. Hammond, Kopa I.E., Zambias R.A., Caldwell C.G., Boger J., Baker, F., Bach T., Luell S., & Macintyre D.E.; "1,3-Dihydro-5-benzofuranols as Antioxidant-Based Inhibitors of Leukotriene Biosynthesis", J. Med. Chem., vol. 32 (1989), pp. 1006-1020.
V. Dauksas et al., "Syntheses and Pharmalogical activity of 5-substituted Coumarans", Khim-Farm. ZH., vol. 22, No. 3, 1988, pp. 303-307 (non English translation).
J.K. Chakrabarti, Eggleton R.J., Gallagher P.T., Harvey J., Hicks, T.A., Kitchen E.A., & Smith C.W.; "5-Acyl-3-Substituted-Benzofuran-2(3H)-Ones as Potential Anti-Inflammatory Agents", J. Med. Chem., vol. 30 (1987), pp. 1663-1668.
V. Dauksas et al., "Synthesis and Antiinflammatory Activity of Acyl-Substituted Benzoxa nd Benzodioxaheterocycles and their Acyclic Analogs", Khim. Farm. ZH., vol. 21, No. 5, 1987, pp. 569-573 (non English translation).
James P. Dunn, et al., "Analgetic and Antiinflammatory 7-Aroylbenzofuran-5-ylacetic Acids and 7-Aroylbenzothiophene-5-ylacetic Acids", Journal Medical Chemistry, vol. 29, 1986, pp. 2326-2329.
O. deMontellano, Correia, P.R., Correia, M.A.; "Suicidal Destruction of Cytochrome P-450 During Oxidative Drug Metabolism", Ann. Rev. Pharmacol. Toxicol., vol. 23 (1983), pp. 481-503.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Dihydrobenzofuran and related compounds useful as anti-inflammat does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Dihydrobenzofuran and related compounds useful as anti-inflammat, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dihydrobenzofuran and related compounds useful as anti-inflammat will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1833362

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.