Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-08-12
1988-03-15
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514231, 514253, 514254, 514324, 514337, 514361, 514383, 514397, 544 585, 544 62, 544132, 544139, 544366, 544370, 546202, 546274, 548127, 548262, 548269, 548336, A01N 4384, C07D40906
Patent
active
047313641
ABSTRACT:
2-Alkyl-, 2-alkenyl- and 2-alkynyl-2,3-dihydro-2-(1H-azolyl(C.sub.1 -C.sub.2)alkyl)benzo[b]thiophenes especially 2-alkyl-, 2-alkenyl- and 2-alkynyl-2,3-dihydro-3-hydroxy-2-(1H-1-imidazolylmethyl)-4-,5-,6- and 7-halobenzo[b]thiophenes and related derivatives having antifungal activity are disclosed. Pharmaceutical compositions comprising compounds of the invention and their use in treating fungal infections in susceptible hosts such as humans are also disclosed.
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patent: 4352808 (1982-10-01), Rane et al.
patent: 4431816 (1984-02-01), Rane et al.
patent: 4496572 (1985-01-01), Cross et al.
C. Djerassi, Steroid Reactions, Holden-Day Inc., 1963, San Francisco, pp. 1-66.
I. T. Harrison, et al., Compendium of Organic Synthetic Methods, Wiley-InterScience, New York, 1971, pp. 449-456.
Pike Russell E.
Rane Dinanath F.
Hoffman Thomas D.
Rosen Gerald S.
Schering Corporation
Schwartz Richard A.
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