Digoxigenine-3-[2',3'-didesoxy-glycosides] and a process for the

Details Digoxigenine-3-[2',3'-didesoxy-glycosides] and a process for the Digoxigenine-3-[2',3'-didesoxy-glycosides] and a process for the

1973-11-16

1976-04-13

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424182, C07J 1900

Patent

active

039503232

ABSTRACT:
Digoxigenine-3-[2', 3'-didesoxy-glycosides] of the formula ##SPC1##
In which R.sup.1 is the digoxigenine radical and R.sup.2 is hydrogen, methyl or --CH.sub.2 OH, which are prepared by a reaction of a digoxigenine-12-monoacylate with an acylated 1,2-glycal, a catalytic hydrogenation of the 12-acylates obtained and a subsequent hydrolysis. The products have a cardiotonic, diuretic and especially venotonic activity.

REFERENCES:
patent: 3642770 (1972-02-01), Haede et al.
patent: 3838146 (1974-09-01), Stache et al.

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