Digital analyte detection system

Details Digital analyte detection system Digital analyte detection system

1992-07-23

1994-07-12

Harvey, Jack B.

Boots, shoes, and leggings

364499, 364555, 324 714, G06G 775

Patent

active

053294610

ABSTRACT:
A system and method for digitally detecting the presence of analyte particles within a sample. Each analyte particle is disposed to emit an optical response upon illumination in a known manner. The digital analyte detection system includes optical apparatus for illuminating a multiplicity of distinct pixel regions within the sample so as to induce each of the analyte particles included therein to emit at least one optical response. The pixel regions are dimensioned such that the number of analyte particles included within each region is less than a maximum detection threshold proportional to variability of the optical responses. The digital detection system further includes apparatus for measuring the emitted signal emitted from each pixel region. A data processing network receives the measurements of the emitted signals and, based on the measurements, counts the number of analyte particles within each pixel region so as to determine the number of analyte particles within the sample.

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