Difluoro statone antiviral analogs

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142318, 5142372, 5142375, 514307, 514314, 514318, 514332, 514357, 514394, 514466, 514486, 514539, 514616, 514619, 514620, 544 78, 544 82, 544131, 544168, 546146, 546170, 546194, 546265, 546335, 546336, 546337, 5483097, 549441, 560 27, 564137, 564138, 564153, 564165, A61K 31535, A61K 31165, C07C23752, C07D26530

Patent

active

059487780

ABSTRACT:
This invention relates to novel statone antiviral analogs, to the processes and intermediates useful for their preparation and to their use as antiviral agents.

REFERENCES:
patent: 5066643 (1991-11-01), Abeles et al.
patent: 5559140 (1996-09-01), Schirlin et al.
Journ. Of Med. Chem. vol. 29, No. 10, pp. 2080-2087 (1986)-S. Thaisrivongs et al. "Design and Synthesis of potent and Specific Renin Inhibitors Containing Difluorostatine, Difluorostatone and Related Analoges".
Journ. Of Med. Chem. vol. 35, No. 1, pp. 2-14 (1992)-A.M. Doherty et al. "Design and Synthesis of Potent, Selective and Orally Active Fluorine Containing Renin Inhibitors".

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