Difluoro keto compounds and their use as HLE inhibitors

Details Difluoro keto compounds and their use as HLE inhibitors Difluoro keto compounds and their use as HLE inhibitors

1987-05-19

1990-05-08

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

514 5, 514 11, 514381, 514423, 548253, 548536, 548537, 548538, A61K 912, A61K 3140, A61K 914, C07D20709

Patent

active

049238906

ABSTRACT:
The invention relates to selected difluoro compounds of formulae Ia, Ib and Ic (set out hereinafter) which are useful as inhibitors of human leukocyte elastase.

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Hammock et al., Biochemistry and Physiology, 17, 76-88 (1982).
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