Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-07-26
1990-06-12
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514274, 514339, 514363, 514359, 514384, A61K 3141, A61K 31505, A61K 3144
Patent
active
049333569
ABSTRACT:
The invention relates to an improved therapy to control intraocular pressure (IOP). More specifically, the present invention relates to an improved treatment of glaucoma patients to control ocular hypertension. It has now been found that an effective amount of diflunisal potentiates the action of certain heterocyclic sulfonamides such as acetazolamide to provide an improved hypotensive therapy.
REFERENCES:
patent: 2554816 (1951-05-01), Clapp et al.
patent: 2980679 (1961-04-01), Pala
patent: 3714226 (1973-01-01), Ruyle et al.
patent: 3991206 (1976-11-01), Tolman et al.
patent: 4305927 (1981-12-01), Theeuwes et al.
patent: 4438123 (1984-03-01), Smith
patent: 4483864 (1984-11-01), Barfknecht et al.
patent: 4619939 (1986-10-01), Maren
patent: 4636515 (1987-01-01), Barfknecht et al.
Verbeeck, R. K. et al., Clin. Pharmacokinet., 8:297 (1983).
Steelman, S. L. et al., Clin. Ther., 1(Suppl):1 (1978).
Tempero, K. F. et al., Br. J. Clin. Pharmacol., 4(Suppl):31S (1977).
Davies, R. O., Pharmacotherapy, 3:9S (1983).
Verbeeck, R. K. et al., Biochem. Pharmacol., 29:571 (1980).
Maren, T. H., J. Pharmacol. Exp. Ther., 130:26 (1980).
Serlin, M. J. et al., Clin. Pharmacol. Ther., 28:493 (1980).
Van Hacken, A. M. et al., Br. J. Clin. Pahrmacol., 20:225 (1985).
Maren, T. H. et al., Invest. Ophthalmol. Vis. Sci., 16:730 (1977).
Weiner, I. M. et al., Bull. Johns Hopkins Hosp., 105:286 (1959).
Sweeney, K. R. et al., Clin. Pharmacol. Ther., 40:518 (1986).
Maren, T. H., Physiol. Rev., 47:595 (1967).
Cornell Research Foundation Inc.
Fay Zohveh A.
Robinson Douglas W.
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