Diflunisal potentiation of acetazolamide in the control of intra

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514274, 514339, 514363, 514359, 514384, A61K 3141, A61K 31505, A61K 3144

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active

049333569

ABSTRACT:
The invention relates to an improved therapy to control intraocular pressure (IOP). More specifically, the present invention relates to an improved treatment of glaucoma patients to control ocular hypertension. It has now been found that an effective amount of diflunisal potentiates the action of certain heterocyclic sulfonamides such as acetazolamide to provide an improved hypotensive therapy.

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