Diffusion through a membrane assaying apparatus and method

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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7386323, 210634, 210640, 210641, 220502, 220529, 435 793, 4352872, 435810, 422 58, 422 61, 422101, 422102, 436164, 436165, 436172, 436177, 436178, 436514, 436536, 436538, G01N 33537, G01N 33558

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055254756

ABSTRACT:
The diffusion through a membrane assaying apparatus and method facilitates rapid detection of small or larger molecular weight substances such as hazardous wastes, toxic chemicals or the like by using a semipermeable membrane having a predetermined molecular weight cutoff. The semipermeable membrane is provided as part of a container having a removable barrier which facilitates control of diffusion through the membrane. The assaying method includes the use of a reaction mechanism for detection of a predetermined substance. The reaction mechanism includes one or more reagents which are designed to either react or compete for a substance for which assaying is being performed. By selecting the proper reagents and molecular weight cutoff of the semipermeable membrane, the presence or absence of a reaction such as a color change or production of vapor provides indication whether the substance being assayed for is present in the test sample.

REFERENCES:
patent: 3948606 (1976-04-01), Johnson
patent: 4266021 (1981-05-01), Nylen et al.
patent: 4663126 (1987-05-01), Gould et al.
patent: 4865813 (1989-09-01), Leon

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