Diffraction grating-based encoded microparticle assay stick

Details Diffraction grating-based encoded microparticle assay stick Diffraction grating-based encoded microparticle assay stick

2011-03-08

2011-03-08

Siefke, Samuel P (Department: 1772)

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Means for analyzing liquid or solid sample

C436S521000, C359S002000, C435S287200

Reexamination Certificate

active

07901630

ABSTRACT:
An assay stick7includes a transparent reaction vessel or tube14having one or more microbeads8disposed therein. The microbeads8have a plurality of unique identification digital codes based on a diffraction grating12disposed therein that are detected when illuminated by incident light24. The incident light24may be directed transversely onto the side or onto an end of the tube14with a narrow band (single wavelength) or multiple wavelength source, in which case the code is represented by a spatial distribution of light or a wavelength spectrum, respectively. The assay stick7may be reused or disposed upon completion of the assay. Alternatively, the beads may be attached to a strip or planar surface. The encoded beads can also provide traceability, quality-control, and authenticity of each bead8to its source and/or to the chemistry on each bead8. Also, the low sample volume of the assay stick allows for faster reactions and better sensitivity.

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