Differentiation of non-insulin producing cells into insulin...

Details Differentiation of non-insulin producing cells into insulin... Differentiation of non-insulin producing cells into insulin...

2006-06-06

2006-06-06

Spector, Lorraine (Department: 1646)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C530S308000

Reexamination Certificate

active

07056734

ABSTRACT:
The present invention relates to a population of insulin producing cells made by a process comprising contacting non-insulin producing cells with a growth factor selected from the group consisting of GLP-1 or Exendin-4, growth factors having amino acid sequences substantially homologous to GLP-1 or Exendin-4, and fragmets thereof. The present invention also relates to methods of differentiating non-insulin producing cells into insulin producing cells and of enriching a population of cells for insulin-producing cells. The present invention also relates to methods of treating diabetes.

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