Chemistry: analytical and immunological testing – Peptide – protein or amino acid
Reexamination Certificate
2011-02-22
2011-02-22
Gakh, Yelena G (Department: 1777)
Chemistry: analytical and immunological testing
Peptide, protein or amino acid
C435S007930
Reexamination Certificate
active
07892844
ABSTRACT:
The present invention relates to a method for differentiating in a subject suffering from acute shortness of breath (dyspnea) between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease or (iv) acute dyspnea without cardiovascular or pulmonary causes comprising the steps of determining the amount of pulmonary surfactant protein B (SP-B) in a sample of a subject, determining the amount of N-terminal pro-brain natriuretic peptide (NT-proBNP) in a sample of the subject, and differentiating between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease or (iv) acute dyspnea without cardiovascular or pulmonary causes by comparing the determined amounts with reference amounts.
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Hess Georg
Horsch Andrea
Adams Michelle M
Gakh Yelena G
Roche Diagnostics Operations Inc.
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