Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1992-06-02
1995-04-11
Saunders, David
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
4351722, 43524027, 436548, 530350, 53038873, 53038875, 5303896, C07K 1528, G01N 33577
Patent
active
054057507
ABSTRACT:
This invention provides a purified new differentiation antigen, designated NDA4, associated with the growth and proliferation of activated B lymphocytes and characterized by a molecular weight of about 46,000 daltons.
The invention also provides an antibody capable of specifically forming a complex with purified NDA4, and a hybridoma which produces a monoclonal antibody that specifically recognizes the isolated NDA4.
The invention also pertains to a method for dectecting B cells or helper T cells, each of which has a B cell growth factor receptor, which comprises contacting a sample which contains B cells or helper T cells with substances capable of forming complexes with the B cell growth factor receptors so as to form cellular complexes between the substances and the B cell growth factor receptors, and detecting such cellular complexes.
REFERENCES:
patent: 4692405 (1987-09-01), Freedman et al.
patent: 4816404 (1989-03-01), Suciu-Foca et al.
patent: 4818689 (1989-04-01), Suciu-Foca et al.
patent: 4831117 (1989-05-01), Uckun
Grant et al, Fed. Proc., 46, 769, 1987.
Greenwood et al, Immunology, 59, 7-13, 1986.
Kikutani et al, Journ. Immunol., 136, 4019-4026, 1986.
Jung et al, Journ. Exp. Med; 160, 1919-1924, 1984.
Suzuki et al, Fed. Proc, 44, 1328, 1985.
Suzuki et al, Journ. Immunol. 137, 1208-1213, 1986.
Suciu-Foca et al, Immunol. Res., 5, 165-172, 1986.
Thorley-Lawson et al, Cell, 30, 415-425, 1982.
Tseng et al, Biol. Abstr., 85, 122386, 1988.
Suciu-Foca, N., et al., J. Immunology, vol. 140, pp. 395-403 (1988).
Suciu-Foca, N., et al., Cellular Immunology, vol. 110, pp. 001-017 (1987).
King Donald W.
Suciu-Foca Nicole
Saunders David
The Trustees of Columbia University in the City of New York
White John P.
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