Differential tumor cytotoxicity compounds and compositions

Details Differential tumor cytotoxicity compounds and compositions Differential tumor cytotoxicity compounds and compositions

2006-10-24

2006-10-24

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C544S166000, C544S329000

Reexamination Certificate

active

07125997

ABSTRACT:
The invention is directed to novel biaryl derivatives, to the uses of these compounds in various medicinal applications, including the treatment, prevention and control of proliferative diseases such as tumors, and to pharmaceutical compositions comprising these compounds. Compounds of the invention can be used to treat or prevent diseases or disorders that involve the activity of MIF-1 and/or adenosine kinase.

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Valgeirsson et al. 2-Arylureidobenzoic Acids: Selective Non-competitive Antagonists for the Homomeric Kainate Receptor Subtype GluR5. J. Med. Chem. 2003, vol. 46, No. 26, pp. 5834-5843.

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