Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus
Reexamination Certificate
2006-03-21
2006-03-21
Choi, Ling-Sui (Department: 1713)
Chemistry: electrical and wave energy
Apparatus
Electrophoretic or electro-osmotic apparatus
C204S600000, C204S450000, C204S547000
Reexamination Certificate
active
07014747
ABSTRACT:
Method and apparatus for dielectrophoretic separation of particles in a fluid based using array of insulating structures arranged in a fluid flow channel. By utilizing an array of insulating structures, a spatially inhomogeneous electric field is created without the use of the embedded electrodes conventionally employed for dielectrophoretic separations. Moreover, by using these insulating structures a steady applied electric field has been shown to provide for dielectrophoresis in contrast to the conventional use of an alternating electric field. In a uniform array of posts, dielectrophoretic effects have been produced flows having significant pressure-driven and electrokinetic transport. Above a threshold applied electric field, filaments of concentrated and rarefied particles appear in the flow as a result of dielectrophoresis. Above a higher threshold applied voltage, dielectrophoresis produces zones of highly concentrated and immobilized particles. These patterns are strongly influenced by the angle of the array of insulating structures with respect to the mean applied electric field and the shape of the insulating structures.
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Cummings et al., “Dielectrophoretic Trapping without Embedded Electrodes”, Proceedings of SPIE, 164-173(2000).
Cummings, et al., “Dielectrophoretic Trapping Without Embedded Electrodes,” Microfluidic Devices and Systems III, Proceedings of SPIE, Sep. 18-19, 2000, vol. 4177, pp. 164-173.
Cummings Eric B.
Singh Anup K.
Choi Ling-Sui
McDonnell Boehnen & Hulbert & Berghoff LLP
Sandia Corporation
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