Dielectrophoretic characterization of micro-organisms and other

Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge

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2041801, 204299R, G01N 2726, G01N 27447

Patent

active

053445350

ABSTRACT:
Dielectrophoretic collection rates of micro-organisms or other animate or inanimate dielectrically polarizable particles in suspension in a fluid are established by flowing the suspension past electrodes energized to produce a non-uniform alternating electric field in the suspension, terminating the energization of the electrodes after a predetermined time to release particles collected from the suspension, and, downstream of the electrodes, measuring the pulse of released particles as a measure of the rate of particle collection during energization of the electrodes. Repeated measurements at different field frequencies enable a collection-rate spectrum to be established and the particles under examination to be characterized or identified by reference to known spectra of known particles.

REFERENCES:
patent: 4326934 (1982-04-01), Pohl
patent: 4476004 (1984-10-01), Pohl
patent: 4578167 (1986-03-01), Schoner
Julian P. H. Burt et al. "An optical dielectrophoresis spectrometer for low-frequency measurements on colloidal suspensions" J. Phys. E: Sci. Instrum 22 (1989) 952-957.
Richard J. Adamson and Karan V. I. S. Kaler "An Automated Stream-Centered Dielectrophoretic System" IEEE Transactions on Industrial Applications, vol. 24, No. 1 (Jan./Feb. 1988) 93-98.
Price et al. "An Optical Technique for Measurement of Cell Dielectrophoresis", 1987, pp. 75-79.
Fujii H., "Measuring Apparatus for Electrophoresis of Suspended Particle", Patent Abstracts of Japan, 1982, vol. 6, No. 62.

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