Dideoxycarbocyclic nucleosides

Details Dideoxycarbocyclic nucleosides Dideoxycarbocyclic nucleosides

1988-01-20

1990-04-10

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544264, 544265, 544267, 544276, 544277, C07D47302, C07D47326, C07D47340, A61K 3152

Patent

active

049162241

ABSTRACT:
Antiviral and antitumor compounds are disclosed of general formula: ##STR1## wherein Z is H, OH or NH.sub.2, Y is CH or N, the bond indicated by C.sub.1 '--C.sub.2 ' is absent or, in combination with the C.sub.1 '--C.sub.2 ' bond is the unit CH.dbd.CH, and X is selected from the group consisting of H, N(R.sub.2), SR, OR or halogen, wherein R is H, lower (C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically acceptable salts thereof.

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