Didemnins and nordidemnins

Details Didemnins and nordidemnins Didemnins and nordidemnins

1990-02-20

1992-08-11

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 11, A61K 3700

Patent

active

051378701

ABSTRACT:
Novel antibiotics didemnins A, B and C (didemnins), and nordidemnins A, B and C (nordidemnins) which can be obtained from a marine organism. These antibiotics are active against a variety of DNA and RNA viruses; thus, they can be used in various environments to control or eradicate these viruses. Further, these antibiotics can be used to treat animals and humans hosting a neoplastic disease.

REFERENCES:
Morishima, et al., Jr. of Antibiotics, vol. XXIII, No. 5, May 1970, pp. 263-265.
Dorr, et al., Clinical Pharmacology (Adult & Pediatric) (Proceedings of Amer. Soc. Clin. Oncol., vol. 5, Mar. 1986), p. 39 (No. 151).
Stewart, et al., Clinical Pharmacology (Adult & Pediatric) (Proceedings of Amer. Soc. Clin. Oncol., vol. 5, Mar. 1986), p. 33 (No. 128).
Jiang, et al., Cancer Chemotherapy & Pharmacology, 1983, vol. 11, No. 4?, pp. 1-4.

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