Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1996-01-19
1999-03-23
Kumar, Shailendra
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514375, 514407, 514485, 514619, 514620, 514621, 514622, 548218, 5483751, 560 27, 564155, 564156, 564165, 564169, 564174, A61K 31165, C07C23305
Patent
active
058860460
ABSTRACT:
This invention relates to chemical compounds that contain adjacent carbonyl groups, which effectively inhibit the biological, chemical, and/or physical properties of enzymes and other medicinally-significant proteins. In particular, the invention relates to dicarbonyl compounds that are capable of acting as enzyme inhibitors, including irreversible inhibitors of HIV-1 protease.
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Anderson Paul
Hirschmann Ralph F.
Smith, III Amos B.
Sprengeler Paul
Yao Wenqing
Kumar Shailendra
The Trustees of the University of Pennsylvania
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