Dicarbamates

Details Dicarbamates Dicarbamates

1983-03-07

1986-01-21

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544320, C07D23948

Patent

active

045658692

ABSTRACT:
Novel pyrimidinedicarbamates of the formula ##STR1## wherein R is lower alkyl or (lower alkyloxy)-(lower alkyl) and X is a leaving group,
can be manufactured by carbamoylating the corresponding free diamines. They are valuable intermediates and can be used, for example, for the manufacture of corresponding oxadiazolopyrimidines of the formula ##STR2## and pharmaceutically acceptable salts thereof. The latter have valuable long-lasting vasodilating and/or bloodpressure lowering properties and are accordingly suitable especially for the treatment of vascular-conditioned hypertensions or as vasodilators in the case of peripheral blood supply disorders.

REFERENCES:
patent: 4175189 (1979-11-01), Muller et al.
Sandler et al., Organic Functional Group Preparations, vol. 11, pp. 244-245 (1971).

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