Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Boron containing doai
Reexamination Certificate
2006-08-01
2006-08-01
Shippen, Michael L. (Department: 1621)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Boron containing doai
C568S005000
Reexamination Certificate
active
07084133
ABSTRACT:
A compound represented by the following general formula (I), wherein R1represents a hydroxy-substituted alkyl group, a hydroxy-substituted alkenyl group, a hydroxy-substituted arylalkyl group (said arylalkyl group may have a substituent on the aryl ring), or a hydroxy-substituted arylalkenyl group (said arylalkenyl group may have a substituent on the aryl ring); X represents a dicarba-closo-dodecaborane-diyl group; R2represents a hydroxy-substituted alkyl group or a hydroxy-substituted alkoxyalkyl group, or a salt thereof, which is useful as an agent exerting vitamin D actions or an agent for enhancing vitamin D actionsin-line-formulae description="In-line Formulae" end="lead"?R1—X—R2.in-line-formulae description="In-line Formulae" end="tail"?
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Ingham et al.,Chemical Abstracts, vol. 76, No. 9, 1972, p. 382, abstract No. 4632.
Fox et al., Transmission of Electronic Effects by Icosahedral Carboranes; Skeletal Carbon—13 Chemical Shifts and Ultraviolet-Visible Spectra of Substitute Aryl-p-carboranes (1,12-dicarba-closo-dodecaboranes),J. Chem. Soc. Dalton Trans., pp. 401-411, 1998.
Zakharkin et al., “Electrophilic and Nucleophilic Constants of o- and m-carboran-1-yl and o-carboran-3-yl groups,” English translation ofZh. Obshch. Khim., vol. 41, pp. 1516-1520, 1971.
English language Abstract of JP 61-76440.
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