Dicalcium phosphate dihydrate with improved stability

Details Dicalcium phosphate dihydrate with improved stability Dicalcium phosphate dihydrate with improved stability

1979-05-29

1981-01-13

Vertiz, O. R.

Chemistry of inorganic compounds

With additive

For stabilizing crystal size or shape

423308, 423311, 423267, 424 57, C01B 2500, C01B 1516, C01B 2526

Patent

active

042449316

ABSTRACT:
Dicalcium phosphate dihydrate containing a sufficient amount of trimagnesium phosphate and/or tetrasodium pyrophosphate to inhibit spontaneous hydrolysis and/or decomposition of the dicalcium phosphate dihydrate is widely used as a dental polishing agent with and without added fluoride. Now it has been found that dicalcium phosphate dihydrate containing a sufficient amount of pyrophosphate to provide hydrolytic stability to the dicalcium phosphate can have improved soluble fluoride stability when at least 0.1 weight percent of trimagnesium phosphate and a pharmaceutically acceptable polyphosphate salt are each added to the formulation. In the preferred embodiment, less than 2 percent pentasodium tripolyphosphate provides satisfactory results.

REFERENCES:
patent: 2852341 (1958-09-01), Bell et al.
patent: 3012852 (1961-12-01), Nelson
patent: 3066056 (1962-11-01), Schlaeger
patent: 3464786 (1969-09-01), Harnisch et al.

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