Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-08-23
1990-12-11
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514410, 546 62, 548421, 548423, A61K 3140, A61K 3144, C07D491044
Patent
active
049771582
ABSTRACT:
The invention relates to novel tetracyclic compounds with an anti-depressant action, without neuroleptic or sedative side effects, of the general formula I ##STR1## and also functional derivatives hereof, wherein: R.sup.1 represents one or two identical or different substituents denoting H, OH, halogen, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy;
R.sup.2 represents one or two identical or different substituents having the same meaning as R.sup.1 ;
R.sup.3 and R.sup.4 are two substituents which are in the cis configuration and of which one is H and the other is OH;
R.sup.5 is H or C.sub.1 -C.sub.4 alkyl;
X denotes O or S;
n is 0 or 1.
REFERENCES:
patent: 4145434 (1979-03-01), van der Burg
patent: 4154836 (1979-05-01), van der Burg
patent: 4158058 (1979-06-01), van der Burg
patent: 4271177 (1981-06-01), van der Burg
patent: 4271179 (1981-06-01), van der Burg
Akzo N.V.
Blackstone William M.
Bobrowicz Donna
Shah Mukund J.
Ward Edward C.
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