Dibenzothiophene derivatives as serum lipid lowering agents

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Allergen or component thereof

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2603293, 424361, 424362, 424363, 424365, A61K 3138

Patent

active

039536017

ABSTRACT:
A compound of the general formula ##SPC1##
And pharmaceutically acceptable salts thereof, in which formula R.sup.0 is H, F, Cl, Br or OCH.sub.3 ; R.sup.1 and R.sup.2 are the same or different and selected from the group consisting of H and alkyl groups having 1-3 carbon atoms; R.sup.3 is H or an alkyl group having 1-3 carbon atoms; R.sup.0 and the side-chain containing the radicals R.sup.1, R.sup.2 and R.sup.3 being placed on the same or different benzene ring. Pharmaceutical preparations containing these compounds are useful in a method for lowering the serum lipid concentration in mammals, including man. These same preparations are also useful for the combined lowering of serum cholesterol and triglyceride concentrations.

REFERENCES:
patent: 3293124 (1966-12-01), Bindler et al.
patent: 3655697 (1972-04-01), Shen et al.
patent: 3704245 (1972-11-01), Umio et al.
patent: 3736334 (1973-05-01), Winter et al.
patent: 3784602 (1974-01-01), Frei et al.

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